Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740348 | 0.88 | CYP4F2 (0.50) | CYP4F2CYP4A11GAAMEN1HPGD | |
| SCHEMBL15287024 | 0.85 | MAPT (0.48) | GAAMEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL31461224 | 0.85 | GAA (0.52) | GAAMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL901696 | 0.85 | CYP4F2 (0.53) | CYP4F2CYP4A11GAAMEN1HPGD | |
| SCHEMBL18524379 | 0.85 | GAA (0.52) | GAAMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL27176902 | 0.84 | CYP4F2 (0.49) | CYP4F2CYP4A11GAAMEN1HPGD | |
| SCHEMBL432804 | 0.82 | CYP4F2 (0.50) | CYP4F2CYP4A11GAAHPGDALDH1A1 | |
| SCHEMBL8361248 | 0.82 | CYP4F2 (0.50) | CYP4F2CYP4A11GAAMEN1HPGD | |
| SCHEMBL16619628 | 0.82 | CYP4F2 (0.50) | CYP4F2CYP4A11GAAHPGDALDH1A1 | |
| SCHEMBL27176866 | 0.82 | CYP4F2 (0.66) | CYP4F2CYP4A11GAAMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898633-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2021-10-27 | — | — | EP | disclosed |
| CN-113474348-A | Substituted oxopyridine derivatives | 拜耳公司 | 2021-10-01 | — | — | CN | disclosed |
| WO-2020127504-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |