Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 9/20 | 0.95 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Fumarate SCHEMBL16619871 | 1.00 | HCAR2 (0.95) | HCAR2CA12AKR1B10CA1CA2 | |
| Isopropyl Fumarate SCHEMBL27790144 | 0.98 | HCAR2 (1.00) | HCAR2CA12AKR1B10CA1CA2 | |
| Isopropyl Fumarate SCHEMBL27941256 | 0.98 | HCAR2 (1.00) | HCAR2CA12AKR1B10CA1CA2 | |
| Maleic Acid SCHEMBL27790143 | 0.98 | HCAR2 (1.00) | HCAR2CA12AKR1B10CA1CA2 | |
| Isopropyl Fumarate SCHEMBL313613 | 0.98 | HCAR2 (1.00) | HCAR2CA12AKR1B10CA1CA2 | |
| Isopropyl Fumarate SCHEMBL690596 | 0.98 | HCAR2 (1.00) | HCAR2CA12AKR1B10CA1CA2 | |
| Isopropyl Fumarate SCHEMBL313612 | 0.98 | HCAR2 (1.00) | HCAR2CA12AKR1B10CA1CA2 | |
| Maleic Acid SCHEMBL27941255 | 0.98 | HCAR2 (1.00) | HCAR2CA12AKR1B10CA1CA2 | |
| Isopropyl Fumarate SCHEMBL1654377 | 0.93 | HCAR2 (0.91) | HCAR2CA12AKR1B10CA1CA2 | |
| Isopropyl Fumarate SCHEMBL10899918 | 0.93 | HCAR2 (0.91) | HCAR2CA12AKR1B10CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052140-A1 | NON-SELF-ADHERENT COATING MATERIALS | Rochal Industries, LLC (US) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015050682-A1 | NON-SELF-ADHERENT COATING MATERIALS | ROCHAL INDUSTRIES, LLP (US) | 2015-04-09 | — | — | WO | disclosed |