Isopropyl Fumarate

Isopropyl Fumarate

SCHEMBL313612

CC(C)OC(=O)/C=C\C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 9/20 1.00
CA12 O43570 1/20 0.46
AKR1B10 O60218 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
AKR1B1 P15121 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
TSHR P16473 3/20 0.45
TP53 P04637 1/20 0.45
EGLN1 Q9GZT9 1/20 0.45
EGLN3 Q9H6Z9 1/20 0.45
ALDH1A1 P00352 2/20 0.43
GAA P10253 1/20 0.43
GABRP O00591 2/20 0.41
GABRD O14764 2/20 0.41
GABRA1 P14867 2/20 0.41
GABRB1 P18505 2/20 0.41
GABRG2 P18507 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropyl Fumarate SCHEMBL27941256 1.00 HCAR2 (1.00) HCAR2CA12AKR1B10CA1CA2
Maleic Acid SCHEMBL27790143 1.00 HCAR2 (1.00) HCAR2CA12AKR1B10CA1CA2
Isopropyl Fumarate SCHEMBL27790144 1.00 HCAR2 (1.00) HCAR2CA12AKR1B10CA1CA2
Maleic Acid SCHEMBL27941255 1.00 HCAR2 (1.00) HCAR2CA12AKR1B10CA1CA2
Isopropyl Fumarate SCHEMBL313613 1.00 HCAR2 (1.00) HCAR2CA12AKR1B10CA1CA2
Isopropyl Fumarate SCHEMBL690596 1.00 HCAR2 (1.00) HCAR2CA12AKR1B10CA1CA2
Isopropyl Fumarate SCHEMBL16619871 0.98 HCAR2 (0.95) HCAR2CA12AKR1B10CA1CA2
Isopropyl Fumarate SCHEMBL16619868 0.98 HCAR2 (0.95) HCAR2CA12AKR1B10CA1CA2
Isopropyl Fumarate SCHEMBL10899918 0.95 HCAR2 (0.91) HCAR2CA12AKR1B10CA1CA2
Isopropyl Fumarate SCHEMBL1654377 0.95 HCAR2 (0.91) HCAR2CA12AKR1B10CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1564 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4683969-A1 COATING COMPOSITIONS AND APPLICATIONS THEREOF Aescula Tech, Inc. (US) 2026-01-28 EP claimed
EP-2196225-B2 Water-soluble agents in acrylate-based preparations BEIERSDORF AG (DE) 2025-04-30 EP claimed
CN-119331340-A Modified EVA material and EVA film production process 上海祥仓包装印刷有限公司 2025-01-21 CN claimed
CN-118978837-A Cutting protection liquid for high-order CIS chip, preparation method and application thereof 浙江奥首材料科技有限公司 2024-11-19 CN claimed
US-12139679-B2 Lubricity modifier for fuels and application thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2024-11-12 US claimed
WO-2024196974-A1 COATING COMPOSITIONS AND APPLICATIONS THEREOF AESCULA TECH, INC. (US) 2024-09-26 WO claimed
US-20240315949-A1 COATING COMPOSITIONS AND APPLICATIONS THEREOF AesculaTech, Inc. 2024-09-26 US claimed
CN-117024729-B High-adhesion polyaspartate, preparation method thereof and polyurea coating 烟台泰和新材高分子新材料研究院有限公司 2024-01-09 CN claimed
CN-117264099-A Ethylene slurry polymerization Ziegler-Natta catalyst component with narrow molecular weight distribution and preparation method thereof 吉化集团吉林市天龙催化剂有限公司 2023-12-22 CN claimed
CN-117024729-A High-adhesion polyaspartate, preparation method thereof and polyurea coating 烟台泰和新材高分子新材料研究院有限公司 2023-11-10 CN claimed
US-5501851-A Emulsion polymers for use in hair fixatives NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1996-03-26 US claimed
US-5426133-A Crosslinked, saponified acrylic copolymers; dimensional and storage stability, heat resistance MENICON CO., LTD. (JP) 1995-06-20 US claimed
EP-0605686-A1 EMULSION POLYMERS FOR USE IN HAIR FIXATIVES National Starch and Chemical Investment Holding Corporation (US) 1994-07-13 EP claimed
EP-0589430-A2 Water-absorptive contact lens Menicon Co., Ltd. (JP) 1994-03-30 EP claimed
WO-1994002112-A1 EMULSION POLYMERS FOR USE IN HAIR FIXATIVES NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1994-02-03 WO claimed
US-5200492-A Copolymer of methyl methacrylate with halophenyl (meth)acrylate and aromatic polycarbonate KURARAY CO., LTD. (JP) 1993-04-06 US claimed
CN-1053811-A The rinse aid that is used for plastic and painted surface HENKEL CORP (US) 1991-08-14 CN claimed
US-4461809-A GRAFT POLYMER OF ETHYLENE, PROPYLENE, AND ALKYL ESTER OF OLEFINIC DICARBOXYLIC ACID MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-07-24 US claimed
US-4366290-A UNSATURATED PEROXYCARBONATE NIPPON OIL AND FATS CO., LTD. (JP) 1982-12-28 US claimed
US-4284707-A Photocurable light-sensitive composition SOMAR MANUFACTURING CO., LTD. (JP) 1981-08-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12139679-B2 Lubricity modifier for fuels and application thereof F12, ACADM, ADH1A HCAR2 341/4885CA12 228/4885AKR1B10 175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.