⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3491358 | 0.83 | — | — | |
| SCHEMBL20548984 | 0.75 | ALOX15 (0.59) | — | |
| SCHEMBL502333 | 0.72 | — | — | |
| SCHEMBL8917412 | 0.70 | — | — | |
| SCHEMBL10689980 | 0.70 | ALOX15 (0.30) | — | |
| Ethylene Glycol SCHEMBL11417061 | 0.67 | TSHR (0.36) | — | |
| SCHEMBL24286985 | 0.67 | — | — | |
| SCHEMBL714191 | 0.65 | — | — | |
| SCHEMBL28195600 | 0.65 | TSHR (0.33) | — | |
| SCHEMBL502288 | 0.65 | ALOX15 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265397-A1 | METHANOL DEHYDROGENASE FUSION PROTEINS | AGAIN BIO APS (DK) | 2023-08-24 | — | — | US | disclosed |
| EP-3368548-B1 | METHANOL DEHYDROGENASE FUSION PROTEINS | GENOMATICA INC (US) | 2023-08-23 | — | — | EP | disclosed |
| US-20230159902-A1 | ALCOHOL DEHYDROGENASE VARIANTS | GENOMATICA, INC. | 2023-05-25 | — | — | US | disclosed |
| US-11384340-B2 | Alcohol dehydrogenase variants | GENOMATICA, INC. (US) | 2022-07-12 | — | — | US | disclosed |
| US-20220177895-A1 | ENGINEERED MICROORGANISMS WITH G3P -> 3PG ENZYME AND/OR FRUCTOSE-1,6-BISPHOSPHATASE INCLUDING THOSE HAVING SYNTHETIC OR ENHANCED METHYLOTROPHY | AGAIN BIO APS (DK) | 2022-06-09 | — | — | US | disclosed |
| EP-3814515-A2 | ENGINEERED MICROORGANISMS WITH G3P---> 3PG ENZYME AND/OR FRUCTOSE-1,6-BISPHOSPHATASE INCLUDING THOSE HAVING SYNTHETIC OR ENHANCED METHYLOTROPHY | Genomatica, Inc. (US) | 2021-05-05 | — | — | EP | disclosed |
| US-20200354692-A1 | ALCOHOL DEHYDROGENASE VARIANTS | AGAIN BIO APS (DK) | 2020-11-12 | — | — | US | disclosed |
| US-10563180-B2 | Alcohol dehydrogenase variants | GENOMATICA, INC. (US) | 2020-02-18 | — | — | US | disclosed |
| US-20190085303-A1 | METHANOL DEHYDROGENASE FUSION PROTEINS | AGAIN BIO APS (DK) | 2019-03-21 | — | — | US | disclosed |
| EP-3368548-A1 | METHANOL DEHYDROGENASE FUSION PROTEINS | Genomatica, Inc. (US) | 2018-09-05 | — | — | EP | disclosed |
| WO-2017075208-A1 | METHANOL DEHYDROGENASE FUSION PROTEINS | GENOMATICA, INC. (US) | 2017-05-04 | — | — | WO | disclosed |
| US-20160237410-A1 | ALCOHOL DEHYDROGENASE VARIANTS | AGAIN BIO APS (DK) | 2016-08-18 | — | — | US | disclosed |
| EP-3052635-A2 | ALCOHOL DEHYDROGENASE VARIANTS | Genomatica, Inc. (US) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015051298-A2 | ALCOHOL DEHYDROGENASE VARIANTS | GENOMATICA, INC. (US) | 2015-04-09 | — | — | WO | disclosed |