Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.54 |
| ▸ | CDC25A | P30304 | 1/20 | 0.51 |
| ▸ | CDC25C | P30307 | 1/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbazole SCHEMBL28181847 | 0.76 | ALDH1A1 (0.61) | PARP1CDC25ACDC25CALDH1A1KDM4E | |
| SCHEMBL25835900 | 0.74 | PARP1 (0.68) | PARP1CDC25ACDC25CGABRPGABRD | |
| SCHEMBL25835901 | 0.74 | PARP1 (0.68) | PARP1CDC25ACDC25CGABRPGABRD | |
| SCHEMBL29380761 | 0.73 | ALDH1A1 (0.68) | PARP1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1635466 | 0.73 | ALDH1A1 (0.68) | PARP1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3151147 | 0.71 | KDM4E (0.50) | PARP1CDC25ACDC25CALDH1A1KDM4E | |
| SCHEMBL10345038 | 0.70 | ALDH1A1 (0.74) | PARP1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29516962 | 0.70 | PARP1 (1.00) | PARP1CHEK1CDK4CCND1MEN1 | |
| SCHEMBL10014083 | 0.70 | PARP1 (0.62) | PARP1CDC25ACDC25CGABRPGABRD | |
| SCHEMBL6214537 | 0.70 | PARP1 (0.62) | PARP1CDC25ACDC25CGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050472-A1 | FUSED INDOLE COMPOUNDS AND METHODS OF USING SAME | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOST'YU "PANACELA LABS" (RU) | 2015-04-09 | — | — | WO | disclosed |