SCHEMBL16620399

SCHEMBL16620399

CCCCCC/C=C\CCCC(=O)NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.72
CNR1 P21554 3/20 0.66
CNR2 P34972 2/20 0.59
SLC6A5 Q9Y345 3/20 0.58
ITGB3 P05106 2/20 0.56
ITGA2B P08514 2/20 0.56
PSMB11 A5LHX3 2/20 0.56
PSMA7 O14818 2/20 0.56
PSMB1 P20618 2/20 0.56
PSMA1 P25786 2/20 0.56
PSMA2 P25787 2/20 0.56
PSMA3 P25788 2/20 0.56
PSMA4 P25789 2/20 0.56
PSMB8 P28062 2/20 0.56
PSMB9 P28065 2/20 0.56
PSMA5 P28066 2/20 0.56
PSMB4 P28070 2/20 0.56
PSMB6 P28072 2/20 0.56
PSMB5 P28074 2/20 0.56
PSMB10 P40306 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16620402 1.00 FAAH (0.72) FAAHCNR1CNR2SLC6A5ITGB3
SCHEMBL424500 0.98 FAAH (0.76) FAAHCNR1CNR2SLC6A5ITGB3
SCHEMBL9954851 0.98 FAAH (0.76) FAAHCNR1CNR2SLC6A5ITGB3
SCHEMBL15649626 0.98 FAAH (0.76) FAAHCNR1CNR2SLC6A5ITGB3
SCHEMBL424499 0.98 FAAH (0.76) FAAHCNR1CNR2SLC6A5ITGB3
SCHEMBL31026947 0.98 FAAH (0.76) FAAHCNR1CNR2SLC6A5ITGB3
SCHEMBL424501 0.98 FAAH (0.76) FAAHCNR1CNR2SLC6A5ITGB3
SCHEMBL26624424 0.97 CNR1 (0.68) FAAHCNR1CNR2SLC6A5PSMB11
SCHEMBL29813833 0.97 CNR1 (0.68) FAAHCNR1CNR2SLC6A5PSMB11
SCHEMBL26624415 0.97 CNR1 (0.68) FAAHCNR1CNR2SLC6A5PSMB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160227824-A1 Organic Compounds GIVAUDAN S.A. (CH) 2016-08-11 US claimed
US-10834950-B2 Organic compounds GIVAUDAN S.A. (CH) 2020-11-17 US disclosed
CN-105592719-B Organic compounds 奇华顿股份有限公司 2020-03-10 CN disclosed
EP-3057447-B1 ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES GIVAUDAN SA (CH) 2017-12-06 EP disclosed
EP-3057447-A1 ORGANIC COMPOUNDS Givaudan S.A. (CH) 2016-08-24 EP disclosed
US-20160227824-A1 Organic Compounds GIVAUDAN S.A. (CH) 2016-08-11 US disclosed
WO-2015050538-A1 ORGANIC COMPOUNDS GIVAUDAN S.A. (CH) 2015-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160227824-A1 Organic Compounds C9, ALKBH3, AOC3 FAAH 914/4885CNR1 206/4885CNR2 331/4885
US-10834950-B2 Organic compounds C9, ALKBH3, AOC3 FAAH 914/4885CNR1 206/4885CNR2 331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.