SCHEMBL16620647

SCHEMBL16620647

O=C(O)CCCCCCCC(=O)NCCCC(=O)O

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.64
EPHX2 P34913 3/20 0.61
KDM4E B2RXH2 1/20 0.60
ADRA1A P35348 1/20 0.59
LMNA P02545 3/20 0.57
TSHR P16473 2/20 0.57
NFKB1 P19838 1/20 0.57
PMP22 Q01453 1/20 0.57
ATM Q13315 1/20 0.53
PLA2G4A P47712 1/20 0.53
MEN1 O00255 1/20 0.53
MAPT P10636 1/20 0.53
KMT2A Q03164 1/20 0.53
SLC6A5 Q9Y345 1/20 0.53
FAAH O00519 2/20 0.52
MAPK1 P28482 1/20 0.52
CNR1 P21554 1/20 0.50
CNR2 P34972 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31317673 1.00 PRMT1 (0.64) PRMT1EPHX2KDM4EADRA1ALMNA
SCHEMBL31317706 1.00 PRMT1 (0.64) PRMT1EPHX2KDM4EADRA1ALMNA
SCHEMBL31317640 1.00 PRMT1 (0.64) PRMT1EPHX2KDM4EADRA1ALMNA
SCHEMBL2811862 0.98 PRMT1 (0.60) PRMT1EPHX2KDM4EADRA1ALMNA
SCHEMBL24483715 0.95 PRMT1 (0.71) PRMT1EPHX2KDM4EADRA1ALMNA
SCHEMBL8766995 0.95 PRMT1 (0.71) PRMT1EPHX2KDM4EADRA1ALMNA
SCHEMBL19646468 0.95 PRMT1 (0.71) PRMT1EPHX2KDM4EADRA1ALMNA
SCHEMBL17767810 0.95 PRMT1 (0.71) PRMT1EPHX2KDM4EADRA1ALMNA
SCHEMBL22506195 0.95 PRMT1 (0.71) PRMT1EPHX2KDM4EADRA1ALMNA
SCHEMBL8507619 0.95 PRMT1 (0.71) PRMT1EPHX2KDM4EADRA1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105658089-B Organic compound 奇华顿股份有限公司 2019-07-09 CN claimed
EP-3057446-B1 ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES GIVAUDAN SA (CH) 2017-12-06 EP claimed
US-20160278408-A1 Organic Compounds GIVAUDAN S.A. (CH) 2016-09-29 US claimed
EP-3057446-A1 ORGANIC COMPOUNDS Givaudan S.A. (CH) 2016-08-24 EP claimed
CN-105658089-A Organic compounds 奇华顿股份有限公司 2016-06-08 CN claimed
WO-2015050537-A1 ORGANIC COMPOUNDS GIVAUDAN S.A. (CH) 2015-04-09 WO claimed
CN-105658089-B Organic compound 奇华顿股份有限公司 2019-07-09 CN disclosed
EP-3057446-B1 ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES GIVAUDAN SA (CH) 2017-12-06 EP disclosed
US-20160278408-A1 Organic Compounds GIVAUDAN S.A. (CH) 2016-09-29 US disclosed
EP-3057446-A1 ORGANIC COMPOUNDS Givaudan S.A. (CH) 2016-08-24 EP disclosed
CN-105658089-A Organic compounds 奇华顿股份有限公司 2016-06-08 CN disclosed
WO-2015050537-A1 ORGANIC COMPOUNDS GIVAUDAN S.A. (CH) 2015-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160278408-A1 Organic Compounds CYC1, AOX1, OR10J3 PRMT1 8/4885EPHX2 2941/4885KDM4E 1322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.