Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PEPD | P12955 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28382904 | 1.00 | ACE (0.53) | ACEACE2L3MBTL1LMNAHSD17B10 | |
| SCHEMBL5035740 | 0.94 | ACE (0.57) | ACEACE2L3MBTL1REN | |
| SCHEMBL5035980 | 0.94 | ACE (0.57) | ACEACE2L3MBTL1REN | |
| SCHEMBL10757058 | 0.94 | ACE (0.57) | ACEACE2L3MBTL1REN | |
| SCHEMBL10537390 | 0.94 | ACE (0.57) | ACEACE2L3MBTL1REN | |
| SCHEMBL10406629 | 0.94 | ACE (0.57) | ACEACE2L3MBTL1REN | |
| SCHEMBL9362232 | 0.94 | ACE (0.57) | ACEACE2L3MBTL1REN | |
| SCHEMBL15650373 | 0.94 | ACE (0.57) | ACEACE2L3MBTL1REN | |
| SCHEMBL21853572 | 0.94 | ACE (0.57) | ACEACE2L3MBTL1REN | |
| SCHEMBL19024592 | 0.94 | ACE (0.57) | ACEACE2L3MBTL1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105592721-B | Organic compounds | 奇华顿股份有限公司 | 2020-03-17 | — | — | CN | disclosed |
| EP-3057449-A1 | ORGANIC COMPOUNDS | Givaudan S.A. (CH) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015050535-A1 | ORGANIC COMPOUNDS | GIVAUDAN S.A. (CH) | 2015-04-09 | — | — | WO | disclosed |
| WO-2015049294-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2015-04-09 | — | — | WO | disclosed |