Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL326803 | 0.91 | NQO1 (0.52) | KDM4ENQO1MAPTNPSR1L3MBTL1 | |
| SCHEMBL25591411 | 0.82 | NQO1 (0.46) | KDM4ENQO1ALDH1A1HPGD | |
| SCHEMBL7666973 | 0.80 | KDM4E (0.49) | KDM4ENQO1MAPTNPSR1L3MBTL1 | |
| SCHEMBL13990807 | 0.80 | KDM4E (0.56) | KDM4ENQO1MAPTNPSR1L3MBTL1 | |
| SCHEMBL5252024 | 0.80 | NQO1 (0.52) | KDM4ENQO1MAPTTSHRALDH1A1 | |
| SCHEMBL3742706 | 0.77 | KDM4E (0.49) | KDM4ENQO1MTNR1AMTNR1BTSHR | |
| SCHEMBL28029625 | 0.77 | KDM4E (0.49) | KDM4ENQO1MAPTMTNR1AMTNR1B | |
| SCHEMBL30072284 | 0.77 | KDM4E (0.49) | KDM4ENQO1MTNR1AMTNR1BTSHR | |
| SCHEMBL10673171 | 0.77 | NQO1 (0.48) | KDM4ENQO1MAPTMTNR1AMTNR1B | |
| SCHEMBL15974948 | 0.76 | KDM4E (0.45) | KDM4ENQO1MAPTMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000224-B1 | Process for the preparation of pillar[5]quinone | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-04-07 | — | — | US | disclosed |