Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 12/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35664 | 0.87 | — | — | |
| SCHEMBL13055391 | 0.84 | TSHR (0.35) | TDP1ACHEEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL28396215 | 0.82 | ACHE (0.57) | ACHEEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL334257 | 0.80 | ACHE (0.37) | ACHEEPHX1 | |
| SCHEMBL7513885 | 0.80 | HTT (0.46) | — | |
| SCHEMBL7966153 | 0.80 | EPHX1 (0.60) | ACHEEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL1416150 | 0.79 | TDP1 (0.47) | TDP1ACHEEPHX1PTGS1KCNH2 | |
| SCHEMBL24386122 | 0.79 | EPHX1 (0.44) | TDP1ACHEEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL3746705 | 0.79 | EPHX1 (0.63) | ACHEEPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL3663444 | 0.79 | EPHX1 (0.63) | ACHEEPHX1ZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999323-B2 | Composition that can be cured by polymerisation for the production of biodegradable, biocompatible, cross-linkable polymers on the basis of polyvinyl alcohol | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2015-04-07 | — | — | US | disclosed |