Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15083918 | 0.89 | CTSC (0.64) | CTSCKCNH2 | |
| SCHEMBL7858106 | 0.83 | CTSC (0.64) | CTSCKCNH2 | |
| SCHEMBL290061 | 0.82 | CTSC (0.73) | CTSCKCNH2 | |
| SCHEMBL15084032 | 0.81 | CTSC (1.00) | CTSC | |
| SCHEMBL15081641 | 0.81 | CTSC (0.62) | CTSC | |
| SCHEMBL19186901 | 0.81 | CTSC (0.62) | CTSC | |
| SCHEMBL31536747 | 0.81 | CTSC (0.60) | CTSC | |
| SCHEMBL31536758 | 0.81 | CTSC (0.60) | CTSC | |
| SCHEMBL31536744 | 0.81 | CTSC (0.60) | CTSC | |
| SCHEMBL15081714 | 0.80 | CTSC (0.59) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999975-B2 | Substituted N- [1-cyano-2- (phenyl) ethyl] -2-azabicyclo [2.2.1] heptane-3-carboxamide inhibitors of cathepsin C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-04-07 | — | — | US | disclosed |