Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24073037 | 0.85 | — | — | |
| SCHEMBL14864006 | 0.74 | GNAI3 (0.41) | GNAI3GNAI1ALDH1A1POLB | |
| SCHEMBL21907248 | 0.74 | GNAI3 (0.41) | GNAI3GNAI1ALDH1A1POLB | |
| SCHEMBL5816229 | 0.74 | GNAI3 (0.41) | GNAI3GNAI1ALDH1A1POLB | |
| SCHEMBL24904293 | 0.73 | — | — | |
| SCHEMBL4342558 | 0.73 | — | — | |
| SCHEMBL3222974 | 0.72 | CYP1A2 (0.59) | GNAI3GNAI1ALDH1A1 | |
| SCHEMBL2693942 | 0.72 | CYP1A2 (0.59) | POLB | |
| SCHEMBL25516579 | 0.72 | CYP1A2 (0.59) | ALDH1A1 | |
| SCHEMBL3976543 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349273-B1 | MODULATORS OF CXCR7 | CHEMOCENTRYX INC (US) | 2015-04-08 | — | — | EP | disclosed |