⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15555619 | 1.00 | — | — | |
| SCHEMBL6515708 | 1.00 | — | — | |
| SCHEMBL11872839 | 0.94 | PRCP (0.40) | — | |
| SCHEMBL10610926 | 0.92 | PRCP (0.39) | — | |
| SCHEMBL9579255 | 0.80 | — | — | |
| SCHEMBL17929302 | 0.80 | — | — | |
| SCHEMBL887204 | 0.80 | — | — | |
| SCHEMBL4630954 | 0.80 | — | — | |
| SCHEMBL5969096 | 0.79 | PRCP (0.42) | — | |
| Proline SCHEMBL28915632 | 0.79 | PRCP (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |
| EP-3002281-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2016-04-06 | — | — | EP | disclosed |
| EP-2857394-A1 | Antiviral compounds | Gilead Pharmasset LLC (US) | 2015-04-08 | — | — | EP | disclosed |