⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7925277 | 0.81 | — | — | |
| SCHEMBL1739747 | 0.76 | — | — | |
| SCHEMBL16970019 | 0.76 | — | — | |
| SCHEMBL3940222 | 0.74 | — | — | |
| SCHEMBL950532 | 0.74 | — | — | |
| SCHEMBL18541784 | 0.74 | — | — | |
| SCHEMBL7754200 | 0.72 | ALDH1A1 (0.64) | — | |
| SCHEMBL7870973 | 0.72 | — | — | |
| SCHEMBL537454 | 0.72 | — | — | |
| SCHEMBL9630187 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277387-B1 | NEW USE OF HISTONE DEACETYLASE INHIBITORS IN CHANGING MRJP3 PROTEIN IN ROYAL JELLY | NATUREWISE BIOTECH & MEDICALS CORP (TW) | 2016-10-19 | — | — | EP | disclosed |
| EP-2045247-B1 | Compounds for the inhibition of histone deacetylase | NATUREWISE BIOTECH & MEDICALS CORP (TW) | 2015-04-08 | — | — | EP | disclosed |