Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | LPL | P06858 | 12/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1129399 | 0.97 | CA1 (0.49) | CA1CA2CA9LPLLIPG | |
| SCHEMBL23575375 | 0.95 | CA1 (0.48) | CA1CA2CA9LPLLIPG | |
| SCHEMBL1129134 | 0.95 | CA1 (0.48) | CA1CA2CA9LPLLIPG | |
| SCHEMBL12099849 | 0.93 | CA1 (0.51) | CA1CA2CA9LPLLIPG | |
| SCHEMBL14230903 | 0.88 | CA1 (0.47) | CA1CA2CA9LPLLIPG | |
| SCHEMBL16291829 | 0.87 | CA1 (0.42) | CA1CA2CA9LPLLIPG | |
| SCHEMBL16291832 | 0.87 | CA1 (0.42) | CA1CA2CA9LPLLIPG | |
| SCHEMBL16291830 | 0.87 | CA1 (0.42) | CA1CA2CA9LPLLIPG | |
| SCHEMBL16308661 | 0.87 | CA1 (0.42) | CA1CA2CA9LPLLIPG | |
| SCHEMBL17962846 | 0.87 | LPL (0.43) | CA1CA2CA9LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133529-A1 | HETEROCYCLIC INHIBITORS OF PCSK9 | Cardio Therapeutics Pty Ltd (AU) | 2022-06-30 | — | — | WO | disclosed |
| EP-2857404-B1 | IMIDAZO[1,2-b]PYRIDAZINE DERIVATIVES AS KINASE INHIBITORS | DAIICHI SANKYO CO LTD (JP) | 2017-08-23 | — | — | EP | disclosed |
| EP-2857404-A1 | IMIDAZO[1,2-b]PYRIDAZINE DERIVATIVE AS KINASE INHIBITOR | Daiichi Sankyo Co., Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |