Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 16/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.49 |
| ▸ | TCF4 | P15884 | 2/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.49 |
| ▸ | CLPP | Q16740 | 2/20 | 0.49 |
| ▸ | TCF7 | P36402 | 2/20 | 0.48 |
| ▸ | BCL9 | O00512 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13028663 | 0.94 | CTNNB1 (0.55) | CYP3A4CTNNB1TCF4CREBBPCLPP | |
| SCHEMBL13028767 | 0.90 | CTNNB1 (0.50) | CYP3A4CTNNB1TCF4CREBBPCLPP | |
| SCHEMBL13028673 | 0.88 | CYP3A4 (0.48) | CYP3A4CTNNB1TCF4CREBBP | |
| SCHEMBL14599264 | 0.88 | CTNNB1 (0.64) | CYP3A4CTNNB1TCF4CREBBPCLPP | |
| SCHEMBL13028677 | 0.87 | CYP3A4 (0.48) | CYP3A4 | |
| SCHEMBL13028664 | 0.87 | CYP3A4 (0.50) | CYP3A4 | |
| SCHEMBL13028771 | 0.87 | CTNNB1 (0.48) | CYP3A4CTNNB1TCF4CREBBPCLPP | |
| SCHEMBL13028674 | 0.86 | CYP3A4 (0.46) | CYP3A4CTNNB1TCF4CREBBP | |
| SCHEMBL747509 | 0.85 | CYP3A4 (0.53) | CYP3A4CTNNB1TCF4CREBBPCLPP | |
| SCHEMBL13028774 | 0.85 | TCF4 (0.46) | CYP3A4CTNNB1TCF4CREBBPCLPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212330-B1 | NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF (3) | CHOONGWAE PHARMA CORP (KR) | 2015-04-08 | — | — | EP | disclosed |