Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.60 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | SELL | P14151 | 1/20 | 0.45 |
| ▸ | SELP | P16109 | 1/20 | 0.45 |
| ▸ | SELE | P16581 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1894742 | 0.82 | TRPV1 (0.82) | ERCC1ERCC4TRPV1ALDH1A1L3MBTL1 | |
| SCHEMBL11269450 | 0.82 | TRPV1 (0.82) | ERCC1ERCC4TRPV1ALDH1A1L3MBTL1 | |
| SCHEMBL6111974 | 0.81 | ERCC1 (0.58) | ERCC1ERCC4TRPV1PTPN1ALDH1A1 | |
| SCHEMBL24521556 | 0.80 | FFAR1 (0.59) | ERCC1ERCC4TRPV1ALDH1A1L3MBTL1 | |
| SCHEMBL6111975 | 0.80 | ERCC1 (0.56) | ERCC1ERCC4TRPV1PTPN1ALDH1A1 | |
| SCHEMBL6111962 | 0.78 | ERCC1 (0.54) | ERCC1ERCC4TRPV1PTPN1ALDH1A1 | |
| SCHEMBL8377106 | 0.75 | TRPV1 (0.61) | ERCC1ERCC4TRPV1ALDH1A1L3MBTL1 | |
| SCHEMBL12993898 | 0.75 | TRPV1 (0.61) | ERCC1ERCC4TRPV1ALDH1A1L3MBTL1 | |
| SCHEMBL26393850 | 0.74 | TRPV1 (1.00) | TRPV1ALDH1A1GAAHDAC2HDAC8 | |
| SCHEMBL1661081 | 0.73 | TRPV1 (0.76) | ERCC1ERCC4TRPV1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212330-B1 | NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF (3) | CHOONGWAE PHARMA CORP (KR) | 2015-04-08 | — | — | EP | disclosed |