Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.71 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8792470 | 0.91 | ALDH1A1 (0.71) | TRPV1GAAALDH1A1L3MBTL1MEN1 | |
| SCHEMBL11269450 | 0.91 | TRPV1 (0.82) | TRPV1GAAALDH1A1L3MBTL1MEN1 | |
| SCHEMBL1894742 | 0.91 | TRPV1 (0.82) | TRPV1GAAALDH1A1L3MBTL1MEN1 | |
| SCHEMBL4075670 | 0.90 | CYP1A2 (0.73) | TRPV1GAAALDH1A1L3MBTL1MEN1 | |
| SCHEMBL17229250 | 0.90 | PLAAT3 (0.73) | TRPV1GAAALDH1A1L3MBTL1MEN1 | |
| SCHEMBL25046063 | 0.90 | ALDH1A1 (0.71) | TRPV1GAAALDH1A1L3MBTL1MEN1 | |
| SCHEMBL29171592 | 0.90 | L3MBTL1 (0.71) | TRPV1GAAALDH1A1L3MBTL1MEN1 | |
| SCHEMBL29171580 | 0.90 | ALDH1A1 (0.71) | TRPV1GAAALDH1A1L3MBTL1MEN1 | |
| SCHEMBL1567314 | 0.90 | SELL (0.69) | TRPV1GAAALDH1A1L3MBTL1MEN1 | |
| SCHEMBL4071835 | 0.90 | CYP1A2 (0.73) | TRPV1GAAALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | claimed |
| WO-1996037485-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | claimed |
| CN-116121782-B | Method for synthesizing tellurium-containing oxazolidinone compound by electrochemically fixing carbon dioxide and application thereof | 桂林电子科技大学 | 2025-04-22 | — | — | CN | disclosed |
| CN-116574154-A | Cyclic peptide-lenalidomide PROTAC derivative, preparation method thereof and application thereof in anticancer drugs | 哈尔滨师范大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-116121782-A | Method for synthesizing tellurium-containing oxazolidinone compound by electrochemically fixing carbon dioxide and application thereof | 桂林电子科技大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-110590691-B | Method for preparing tetra-substituted vinyl oxazolidine-2, 4-diketone from carbon dioxide | 常州大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-110066254-B | Preparation method of isothiazole-3-ketone compound | 温州大学 | 2021-03-19 | — | — | CN | disclosed |
| CN-107790186-B | Novel decamethyl cyclopentadienyl zirconium complex and preparation method and application thereof | 山西医科大学 | 2020-10-30 | — | — | CN | disclosed |
| CN-109180601-B | Organic amine catalyzed CO2Method for synthesizing 2, 4-oxazolidinedione compound | 大连理工大学 | 2020-08-21 | — | — | CN | disclosed |
| CN-110590691-A | Method for preparing tetra-substituted vinyl oxazolidine-2, 4-diketone from carbon dioxide | 常州大学 | 2019-12-20 | — | — | CN | disclosed |
| US-9757375-B2 | Compounds that inhibit human DNA ligases and methods of treating cancer | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2017-09-12 | — | — | US | disclosed |
| US-20050032793-A1 | 2-amino-benzoxazinones for the treatment of viral infections | G.D. SEARLE & CO. (US) | 2005-02-10 | — | — | US | disclosed |
| US-20040259890-A1 | Spiro compounds | MSD K.K. (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1122245-B1 | 2-Amino-benzoxazinones for the treatment of viral infections | SEARLE & CO (US) | 2004-07-07 | — | — | EP | disclosed |
| EP-1415986-A1 | SPIRO COMPOUNDS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | EP | disclosed |
| EP-1122245-A2 | 2-Amino-benzoxazinones for the treatment of viral infections | G.D. Searle & Co. (US) | 2001-08-08 | — | — | EP | disclosed |
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | disclosed |
| EP-0773929-A1 | PIPERIDINE DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996039386-A1 | PIPERIDINE DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1996-12-12 | — | — | WO | disclosed |
| WO-1996037485-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032793-A1 | 2-amino-benzoxazinones for the treatment of viral infections | IFNAR1, IL4I1, ACE2 | TRPV1 2053/4885GAA 2790/4885ALDH1A1 1858/4885 |
| US-20040259890-A1 | Spiro compounds | OPRD1, PER2, OPRK1 | TRPV1 682/4885GAA 2357/4885ALDH1A1 1250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.