Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.77 |
| ▸ | SCD | O00767 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1985009 | 0.95 | SCD (0.67) | APPSCDNPC1RAB9AMEN1 | |
| SCHEMBL16623336 | 0.92 | MAPT (0.64) | APPSCDNPC1RAB9AMEN1 | |
| SCHEMBL2193639 | 0.92 | APP (0.63) | APPSCDNPC1RAB9AMEN1 | |
| SCHEMBL2191507 | 0.91 | APP (0.71) | APPSCDNPC1RAB9AMEN1 | |
| SCHEMBL2192963 | 0.91 | APP (0.71) | APPSCDNPC1RAB9AMEN1 | |
| SCHEMBL1983311 | 0.90 | MMP2 (0.69) | APPSCDNPC1RAB9AMEN1 | |
| SCHEMBL2193573 | 0.90 | APP (0.60) | APPSCDNPC1RAB9AMEN1 | |
| SCHEMBL2196579 | 0.89 | APP (0.59) | APPSCDNPC1RAB9AMEN1 | |
| SCHEMBL12509332 | 0.89 | APP (0.59) | APPSCDNPC1RAB9AMEN1 | |
| SCHEMBL2192191 | 0.89 | APP (0.72) | APPSCDNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338059-B1 | Ligands for aggregated tau molecules | WISTA LAB LTD (SG) | 2015-04-08 | — | — | EP | disclosed |