Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SCD | O00767 | 2/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2192766 | 0.85 | SCD (0.56) | APPSCDHTTMEN1RAB9A | |
| SCHEMBL16623340 | 0.78 | APP (0.57) | APPGLAGAAHSD17B1HSD17B2 | |
| SCHEMBL2195686 | 0.77 | SCD (0.54) | APPGLAGAASCDHTT | |
| SCHEMBL2000049 | 0.77 | SCD (0.59) | APPSCDHTTMEN1RAB9A | |
| SCHEMBL2196123 | 0.76 | SCD (0.57) | APPSCDHTTMEN1RAB9A | |
| SCHEMBL3612693 | 0.75 | APP (0.53) | APPGLAGAASCDCYP3A4 | |
| SCHEMBL28034624 | 0.75 | DYRK1A (0.50) | APPSCDRAB9ASULT1A1NPC1 | |
| SCHEMBL2193132 | 0.75 | SCD (0.56) | APPGAASCDHTTMEN1 | |
| SCHEMBL2195831 | 0.75 | SCD (0.56) | APPSCDHTTMEN1RAB9A | |
| SCHEMBL1999194 | 0.75 | MAPT (0.64) | APPSCDALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338059-B1 | Ligands for aggregated tau molecules | WISTA LAB LTD (SG) | 2015-04-08 | — | — | EP | disclosed |