Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2192465 | 0.84 | PLG (0.61) | APPGAAMAPTCSNK1D | |
| SCHEMBL16623335 | 0.78 | APP (0.54) | APPGLAGAAHSD17B1HSD17B2 | |
| SCHEMBL2196579 | 0.76 | APP (0.59) | APPMAPTCSNK1D | |
| SCHEMBL12509545 | 0.76 | APP (0.58) | APPGLAGAASULT1A1MAPT | |
| SCHEMBL10032141 | 0.74 | APP (1.00) | APPGLAGAASULT1A1 | |
| SCHEMBL2119782 | 0.74 | APP (1.00) | APPGLAGAASULT1A1 | |
| SCHEMBL2195119 | 0.74 | MAPT (0.75) | APPGLAGAAMAPT | |
| SCHEMBL2194534 | 0.73 | APP (0.59) | APPGLAGAAMAPTCSNK1D | |
| SCHEMBL2192191 | 0.72 | APP (0.72) | APPGLAGAAMAPT | |
| SCHEMBL13853554 | 0.72 | APP (0.95) | APPGLAGAASULT1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338059-B1 | Ligands for aggregated tau molecules | WISTA LAB LTD (SG) | 2015-04-08 | — | — | EP | disclosed |