Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 17/20 | 0.62 |
| ▸ | SULT1A1 | P50225 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1982573 | 0.92 | APP (0.62) | APPSULT1A1MAPTKDM4ENPC1 | |
| SCHEMBL1982572 | 0.92 | APP (0.62) | APPSULT1A1MAPTKDM4ENPC1 | |
| SCHEMBL2922465 | 0.92 | APP (0.72) | APPSULT1A1MAPTKDM4ENPC1 | |
| SCHEMBL12422080 | 0.90 | APP (0.59) | APPSULT1A1MAPTKDM4ENPC1 | |
| SCHEMBL16623332 | 0.89 | MAPT (0.68) | APPMAPTKDM4ENPC1GLA | |
| SCHEMBL28095214 | 0.88 | APP (0.63) | APPSULT1A1MAPTKDM4ENPC1 | |
| SCHEMBL1984686 | 0.86 | APP (0.84) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL1984683 | 0.86 | APP (0.84) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL12421901 | 0.86 | APP (0.84) | APPSULT1A1MAPTKDM4ENPC1 | |
| SCHEMBL1987223 | 0.86 | APP (0.55) | APPSULT1A1MAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338059-B1 | Ligands for aggregated tau molecules | WISTA LAB LTD (SG) | 2015-04-08 | — | — | EP | disclosed |