Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 2/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16623471 | 0.84 | CCNE2 (0.39) | BRD4 | |
| SCHEMBL16623452 | 0.74 | BRD9 (0.31) | — | |
| SCHEMBL16611521 | 0.70 | CA12 (0.39) | — | |
| SCHEMBL16726660 | 0.68 | ALDH1A1 (0.47) | — | |
| SCHEMBL16623514 | 0.66 | BRD9 (0.39) | — | |
| SCHEMBL16623513 | 0.65 | SRC (0.38) | — | |
| SCHEMBL16623539 | 0.65 | BRD9 (0.32) | — | |
| SCHEMBL16726643 | 0.63 | GSK3B (0.40) | — | |
| SCHEMBL16623549 | 0.61 | LCK (0.38) | RET | |
| SCHEMBL16623441 | 0.61 | JAK2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857400-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |