Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11183646 | 0.91 | TDP1 (0.46) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL3310243 | 0.83 | KDM4E (0.48) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL976216 | 0.82 | HDAC6 (0.55) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL16396046 | 0.82 | TDP1 (0.47) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL3441905 | 0.81 | HDAC6 (0.54) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL11173311 | 0.80 | L3MBTL1 (0.50) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL7801200 | 0.80 | HDAC6 (0.70) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8068658 | 0.78 | KDM4E (0.44) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL11178846 | 0.78 | KDM4E (0.48) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL11176901 | 0.78 | KDM4E (0.48) | KDM4ETDP1ALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053917-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | Nissan Chemical Industries, Ltd. (JP) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015050212-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | 日産化学工業株式会社 | 2015-04-09 | — | — | WO | disclosed |