Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | BCHE | P06276 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662002 | 0.90 | NAAA (0.52) | NAAANAMPTACHEBCHEHSD17B10 | |
| SCHEMBL1661989 | 0.89 | NAAA (0.48) | NAAANAMPTACHEBCHEHSD17B10 | |
| SCHEMBL1661986 | 0.89 | NAAA (0.48) | NAAANAMPTACHEBCHEHSD17B10 | |
| SCHEMBL1662272 | 0.89 | NAAA (0.51) | NAAANAMPTACHEBCHEHSD17B10 | |
| SCHEMBL1657096 | 0.86 | CA12 (0.47) | ACHEBCHEHSD17B10ALDH1A1KMT2A | |
| SCHEMBL1662173 | 0.85 | NAAA (0.44) | NAAANAMPTACHEBCHEHSD17B10 | |
| SCHEMBL1661999 | 0.85 | NAAA (0.44) | NAAANAMPTACHEBCHEHSD17B10 | |
| SCHEMBL1662010 | 0.85 | NAAA (0.44) | NAAANAMPTACHEBCHEHSD17B10 | |
| SCHEMBL1662009 | 0.85 | NAAA (0.44) | NAAANAMPTACHEBCHEHSD17B10 | |
| SCHEMBL1662262 | 0.84 | NAAA (0.43) | NAAANAMPTACHEBCHEHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044138-A1 | LIPOIC ACID ACYLATED SALICYLATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2011-04-14 | — | — | WO | disclosed |