Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 12/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | POLG | P54098 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16617509 | 0.91 | FDPS (0.46) | HPRT1FGFR1FDPSFGFR4CYP1A2 | |
| SCHEMBL16625397 | 0.88 | FDPS (0.42) | HPRT1FGFR1FDPSFGFR4CYP1A2 | |
| SCHEMBL16625382 | 0.88 | FDPS (0.43) | HPRT1FGFR1FDPSFGFR4CYP1A2 | |
| SCHEMBL16625364 | 0.88 | HPRT1 (0.45) | HPRT1 | |
| SCHEMBL16625376 | 0.85 | FDPS (0.46) | HPRT1FGFR1FDPSFGFR4 | |
| SCHEMBL16625386 | 0.84 | HPRT1 (0.64) | HPRT1 | |
| SCHEMBL15531936 | 0.83 | HPRT1 (0.52) | HPRT1FGFR1FDPSFGFR4 | |
| SCHEMBL16625380 | 0.82 | HPRT1 (0.50) | HPRT1FGFR1FDPSFGFR4CYP1A2 | |
| SCHEMBL19245713 | 0.82 | FDPS (0.39) | HPRT1SLC22A6ABCB11POLA1POLG | |
| SCHEMBL16625384 | 0.82 | HPRT1 (0.52) | HPRT1FGFR1FDPSFGFR4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9200020-B2 | 6-oxopurine phosphoribosyltransferase inhibitors | THE UNIVERSITY OF QUEENSLAND (AU) | 2015-12-01 | — | — | US | disclosed |
| US-20150099722-A1 | 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099722-A1 | 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS | HPRT1, APRT, TPMT | HPRT1 1/4885SLC22A6 422/4885ABCB11 1061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.