Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDR | P35968 | 5/20 | 0.58 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KDM6B | O15054 | 1/20 | 0.54 |
| ▸ | KDM4A | O75164 | 1/20 | 0.54 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.54 |
| ▸ | FLT1 | P17948 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16625615 | 0.91 | KDM4C (0.64) | ALDH1A1KDRKDM4CKDM4EKDM6B | |
| SCHEMBL15528663 | 0.85 | KMT2A (0.54) | ALDH1A1KDRKDM4EMAPTNPSR1 | |
| SCHEMBL4979677 | 0.85 | KDR (0.71) | ALDH1A1KDRFLT1MAPTNAMPT | |
| SCHEMBL1585595 | 0.80 | KDM4C (0.55) | ALDH1A1KDRKDM4CKDM4EKDM6B | |
| SCHEMBL2511447 | 0.79 | KDM4C (0.78) | ALDH1A1KDM4CKDM4EKDM6BKDM4A | |
| SCHEMBL15542774 | 0.78 | SMN1; SMN2 (0.52) | ALDH1A1KDRKDM4EMAPTNAMPT | |
| SCHEMBL27847518 | 0.78 | KDM4C (0.67) | ALDH1A1KDM4CKDM4EKDM6BKDM4A | |
| SCHEMBL4977683 | 0.77 | KDR (0.71) | KDRFLT1NAMPTHTTKIT | |
| SCHEMBL1523353 | 0.77 | KDM4C (0.62) | ALDH1A1KDM4CKDM4EKDM6BKDM4A | |
| SCHEMBL16625628 | 0.77 | KDR (0.84) | ALDH1A1KDRKDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150099758-A1 | Alpha 7 Nicotinic Acetylcholine Receptor Allosteric Modulators, Their Derivatives and Uses Thereof | ANVYL LLC (US) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099758-A1 | Alpha 7 Nicotinic Acetylcholine Receptor Allosteric Modulators, Their Derivatives and Uses Thereof | CHRNA7, CHRNA1, CHRNA2 | ALDH1A1 2093/4885KDR 4467/4885KDM4C 3149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.