Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16131457 | 0.85 | KDM4E (0.43) | MEN1KMT2AMAPTTP53LMNA | |
| SCHEMBL16131496 | 0.83 | MAPT (0.44) | MEN1KMT2AMAPTTP53LMNA | |
| SCHEMBL16098301 | 0.82 | POLB (0.57) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL16131528 | 0.81 | MEN1 (0.51) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL3223243 | 0.76 | MAPT (0.57) | MEN1KMT2AMAPTTP53LMNA | |
| SCHEMBL16131507 | 0.75 | MAPT (0.56) | MAPTTP53LMNAGRM2POLB | |
| SCHEMBL5308816 | 0.74 | HTR2A (0.47) | MEN1KMT2AMAPTTP53LMNA | |
| SCHEMBL16454261 | 0.73 | GABRP (0.46) | MEN1KMT2ALMNAPOLBABCG2 | |
| SCHEMBL16131495 | 0.72 | MEN1 (0.56) | MEN1KMT2APOLBABCG2P2RX4 | |
| SCHEMBL16101686 | 0.72 | MEN1 (0.54) | MEN1KMT2AMAPTPOLBABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050471-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USING SAME | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOST'YU "PANACELA LABS" (RU) | 2015-04-09 | — | — | WO | disclosed |