SCHEMBL16626939

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19889032	0.89	NAMPT (0.61)	NAMPTCA2CA1CNR1CYP17A1
	SCHEMBL19889037	0.88	NAMPT (0.60)	NAMPTCA2CA1CNR1FPR2
	SCHEMBL19889238	0.88	NAMPT (0.60)	NAMPTCA2CA1CNR1CYP17A1
	SCHEMBL23963303	0.86	NAMPT (0.57)	NAMPTCA2CA1CNR1CYP17A1
	SCHEMBL16193024	0.85	NAMPT (0.62)	NAMPTCA2CA1CYP17A1HTT
	SCHEMBL1438420	0.84	NPC1 (0.53)	NAMPTCA2CA1CYP17A1HTT
	SCHEMBL2728636	0.84	NAMPT (0.55)	NAMPTCA2CA1CNR1IGF1R
	SCHEMBL27478755	0.83	NAMPT (0.57)	NAMPTCA2CA1CNR1NPC1
	SCHEMBL7015585	0.83	NAMPT (0.59)	NAMPTCA2CA1CYP17A1NPC1
	SCHEMBL23291267	0.83	CYP17A1 (0.57)	NAMPTCA2CA1CYP17A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.