Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15599542 | 0.88 | NAMPT (0.56) | NAMPTCA2CA1LMNAMAPT | |
| SCHEMBL23291264 | 0.86 | NAMPT (0.57) | NAMPTCA2CA1LMNAMAPT | |
| SCHEMBL23291280 | 0.85 | NAMPT (0.54) | NAMPTCA2CA1LMNAMAPT | |
| SCHEMBL23291263 | 0.84 | NAMPT (0.53) | NAMPTCA2CA1LMNAMAPT | |
| SCHEMBL16626939 | 0.84 | NAMPT (0.61) | NAMPTCA2CA1LMNACNR1 | |
| SCHEMBL7015585 | 0.83 | NAMPT (0.59) | NAMPTCA2CA1LMNAMAPT | |
| SCHEMBL4867801 | 0.82 | NAMPT (0.58) | NAMPTCA2CA1MAPTIDO1 | |
| SCHEMBL1438370 | 0.81 | CYP17A1 (0.50) | NAMPTCA2CA1 | |
| SCHEMBL14326995 | 0.81 | CA2 (0.55) | NAMPTCA2CA1LMNACTSK | |
| SCHEMBL21521028 | 0.81 | CA2 (0.55) | NAMPTCA2CA1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012058325-A1 | COMPOUNDS AND METHODS USEFUL FOR TREATMENT OF DISEASES MEDIATED BY HIF-1 | ONCOTHYREON INC. (US) | 2012-05-03 | — | — | WO | disclosed |