SCHEMBL16627168

SCHEMBL16627168

Cc1cc(-c2nn(C)c(Cl)c2C)ccc1OCc1c(Cl)cccc1-n1nnn(C)c1=O

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 4/20 0.37
MRGPRX4 Q96LA9 3/20 0.33
VDR P11473 1/20 0.31
MAPT P10636 1/20 0.31
RIPK1 Q13546 1/20 0.31
MET P08581 1/20 0.31
EPHA2 P29317 1/20 0.30
KDR P35968 1/20 0.30
S1PR5 Q9H228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16627153 0.94 NR1H4 (0.33) NR1H4MRGPRX4MAPT
SCHEMBL16911192 0.93 NR1H4 (0.37) NR1H4MRGPRX4VDRMAPTMET
SCHEMBL16911097 0.91 NR1H4 (0.32) NR1H4MRGPRX4
SCHEMBL16627154 0.91 TP53 (0.33) NR1H4MRGPRX4MAPTEPHA2KDR
SCHEMBL16910785 0.91 MAPT (0.33) NR1H4MRGPRX4MAPT
SCHEMBL16627971 0.91 NR1H4 (0.32) NR1H4MRGPRX4MAPT
SCHEMBL16911787 0.91 PTGER1 (0.35) NR1H4MRGPRX4MAPT
SCHEMBL16911646 0.91 NR1H4 (0.36) NR1H4MRGPRX4MAPT
SCHEMBL16911502 0.91 NR1H4 (0.36) NR1H4MRGPRX4VDRMAPT
SCHEMBL16910665 0.91 NR1H4 (0.36) NR1H4MRGPRX4VDRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9828389-B2 Tetrazolinone compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-28 US disclosed
US-9828389-B2 Tetrazolinone compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-28 US disclosed
US-9828389-B2 Tetrazolinone compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-28 US disclosed
EP-2900655-B1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2017-05-10 EP disclosed
EP-2900655-B1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2017-05-10 EP disclosed
US-20150203511-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-23 US disclosed
US-20150203511-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-23 US disclosed
US-20150203511-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-23 US disclosed
WO-2015050040-A1 PLANT DISEASE CONTROL COMPOSITION AND USE THEREOF 住友化学株式会社 2015-04-09 WO disclosed
WO-2015050039-A1 PLANT DISEASE CONTROL COMPOSITION AND USE THEREOF 住友化学株式会社 2015-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150203511-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES CYCS, MT-CO3, CYP4F11 NR1H4 1326/4885MRGPRX4 1919/4885VDR 712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.