Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10201391 | 0.88 | BTK (0.44) | BTK | |
| SCHEMBL16014353 | 0.86 | BTK (0.40) | BTK | |
| SCHEMBL611319 | 0.86 | BTK (0.57) | BTK | |
| SCHEMBL16248113 | 0.76 | BTK (0.58) | BTK | |
| SCHEMBL13964669 | 0.75 | BTK (0.57) | BTK | |
| SCHEMBL12503526 | 0.75 | BTK (0.57) | BTK | |
| Potassium Ion SCHEMBL626696 | 0.74 | BTK (0.57) | BTK | |
| SCHEMBL16014489 | 0.74 | BTK (0.42) | BTK | |
| SCHEMBL15578691 | 0.73 | BTK (0.53) | BTK | |
| SCHEMBL14878000 | 0.73 | NPBWR1 (0.39) | BTKNPBWR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050703-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | CHEN YI (US) | 2015-04-09 | — | — | WO | disclosed |