Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16638481 | 0.89 | USP2 (0.46) | USP2TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL5111690 | 0.88 | TSHR (0.52) | USP2TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL17792592 | 0.87 | TSHR (0.44) | USP2TSHRHTTMEN1THRB | |
| SCHEMBL12137915 | 0.86 | USP2 (0.41) | USP2TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL13069406 | 0.86 | USP2 (0.41) | USP2TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL18081989 | 0.85 | USP2 (0.40) | USP2TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL14747652 | 0.85 | USP2 (0.55) | USP2TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL10990567 | 0.85 | USP2 (0.55) | USP2TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL13497241 | 0.85 | TSHR (0.47) | USP2TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL13843481 | 0.85 | USP2 (0.50) | USP2TSHRLPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150098903-A1 | Compounds and Compositions for the Detection and Treatment of Alzheimer's Disease and Related Disorders | THE GENERAL HOSPITAL CORPORATION | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150098903-A1 | Compounds and Compositions for the Detection and Treatment of Alzheimer's Disease and Related Disorders | APP, PSEN1, PSEN2 | USP2 3517/4885TSHR 4451/4885LPAR1 1156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.