Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3489235 | 0.93 | GPR119 (0.78) | GPR119POLBBLMTDP1KMT2A | |
| SCHEMBL3488667 | 0.89 | GPR119 (0.73) | GPR119POLBBLMTDP1KMT2A | |
| SCHEMBL1118210 | 0.89 | GPR119 (0.75) | GPR119POLBBLMTDP1KMT2A | |
| SCHEMBL1118281 | 0.89 | GPR119 (0.75) | GPR119POLBBLMTDP1KMT2A | |
| SCHEMBL1118551 | 0.89 | GPR119 (0.75) | GPR119POLBBLMTDP1KMT2A | |
| SCHEMBL1664563 | 0.88 | GPR119 (1.00) | GPR119POLBBLMTDP1KMT2A | |
| SCHEMBL3489731 | 0.88 | GPR119 (0.74) | GPR119POLBBLMTDP1KMT2A | |
| SCHEMBL3488039 | 0.88 | GPR119 (0.79) | GPR119POLBBLMTDP1KMT2A | |
| SCHEMBL14874881 | 0.87 | GPR119 (0.71) | GPR119POLBBLMTDP1KMT2A | |
| SCHEMBL3489359 | 0.87 | GPR119 (0.78) | GPR119POLBBLMTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483281-A1 | SUBSTITUTED TETRAZOL-1-YL-PHENOXYMETHYL-THIAZOL-2-YL-PIPERIDINYL-PYRIMIDINE SALTS | Metabolex Inc. (US) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011041154-A1 | SUBSTITUTED TETRAZOL-1-YL-PHENOXYMETHYL-THIAZOL-2-YL-PIPERIDINYL-PYRIMIDINE SALTS | METABOLEX, INC. (US) | 2011-04-07 | — | — | WO | disclosed |