Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627777 | 0.91 | SMN1; SMN2 (0.58) | MEN1KMT2AKDM4ELMNAGAA | |
| SCHEMBL16627596 | 0.90 | KMT2A (0.52) | MEN1KMT2AKDM4ELMNAGAA | |
| SCHEMBL16627893 | 0.89 | KMT2A (0.51) | MEN1KMT2AKDM4ELMNAGAA | |
| SCHEMBL16627842 | 0.89 | KMT2A (0.51) | MEN1KMT2AKDM4ELMNAGAA | |
| SCHEMBL16627838 | 0.89 | KMT2A (0.51) | MEN1KMT2AKDM4ELMNAGAA | |
| SCHEMBL16627597 | 0.86 | KMT2A (0.48) | MEN1KMT2AKDM4ELMNAGAA | |
| SCHEMBL16627849 | 0.85 | ALDH1A1 (0.57) | MEN1KMT2AKDM4ELMNAGAA | |
| SCHEMBL16627895 | 0.84 | MEN1 (0.58) | MEN1KMT2AKDM4ELMNAGAA | |
| SCHEMBL34468718 | 0.80 | KDM4E (0.62) | MEN1KMT2AKDM4ELMNAGAA | |
| SCHEMBL7349368 | 0.76 | BRD4 (0.53) | MEN1KMT2AKDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |