Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 1/20 | 0.57 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PDE2A | O00408 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34468710 | 0.92 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL34468745 | 0.88 | KMT2A (0.65) | KDM4EALDH1A1HPGDHSD17B10EGLN1 | |
| SCHEMBL16627711 | 0.88 | HTT (0.57) | KDM4EALDH1A1HPGDHSD17B10CNR1 | |
| SCHEMBL34468782 | 0.88 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10CNR1 | |
| SCHEMBL16627888 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL34468828 | 0.84 | MAPT (0.62) | KDM4EALDH1A1HPGDHSD17B10CNR1 | |
| SCHEMBL31653933 | 0.84 | ERCC1 (0.54) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL34468871 | 0.83 | SMN1; SMN2 (0.52) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL34468780 | 0.83 | SMYD3 (0.48) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL34468864 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |