SCHEMBL16627711

SCHEMBL16627711

O=C(NCc1ccc(F)cc1)c1cc2ccccc2[nH]c1=O

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
KMT2A Q03164 3/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2C19 P33261 1/20 0.54
EGLN1 Q9GZT9 1/20 0.54
KDM4E B2RXH2 4/20 0.52
HSD17B10 Q99714 2/20 0.52
ALDH1A1 P00352 2/20 0.52
HPGD P15428 1/20 0.52
MEN1 O00255 2/20 0.52
CNR2 P34972 2/20 0.51
LMNA P02545 3/20 0.50
MAPT P10636 2/20 0.48
SMYD3 Q9H7B4 1/20 0.48
CNR1 P21554 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34468710 0.90 KDM4E (0.64) SMN1; SMN2KMT2AKDM4EHSD17B10ALDH1A1
SCHEMBL34468780 0.88 SMYD3 (0.48) HTTSMN1; SMN2KMT2AKDM4EHSD17B10
SCHEMBL34468789 0.88 KDM4E (0.55) KMT2AKDM4EHSD17B10ALDH1A1HPGD
SCHEMBL16627713 0.88 CNR2 (0.59) SMN1; SMN2KMT2AKDM4EALDH1A1CNR2
SCHEMBL34468745 0.88 KMT2A (0.65) KMT2AEGLN1KDM4EHSD17B10ALDH1A1
SCHEMBL34468782 0.88 KDM4E (0.58) HTTSMN1; SMN2KMT2AKDM4EHSD17B10
SCHEMBL16627730 0.88 GALR3 (0.57) KMT2AEGLN1KDM4EHSD17B10ALDH1A1
SCHEMBL34468828 0.84 MAPT (0.62) SMN1; SMN2KMT2AKDM4EHSD17B10ALDH1A1
SCHEMBL16627888 0.84 KDM4E (0.49) KMT2AKDM4EHSD17B10ALDH1A1HPGD
SCHEMBL31653933 0.84 ERCC1 (0.54) KMT2AKDM4EHSD17B10ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090571-A1 APYRASE INHIBITORS TEXAS CROP SCIENCE, INC. (US) 2026-04-30 WO claimed
US-20260116873-A1 APYRASE INHIBITORS TEXAS CROP SCIENCE INC (US) 2026-04-30 US claimed
WO-2026090571-A1 APYRASE INHIBITORS TEXAS CROP SCIENCE, INC. (US) 2026-04-30 WO disclosed
US-20260116873-A1 APYRASE INHIBITORS TEXAS CROP SCIENCE INC (US) 2026-04-30 US disclosed
WO-2015050379-A1 NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF 광주과학기술원 2015-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116873-A1 APYRASE INHIBITORS APEH, AP3M1, SRR HTT 4290/4885SMN1; SMN2 4569/4885KMT2A 2697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.