Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | DDO | Q99489 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627574 | 0.87 | BRD4 (0.57) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL16627578 | 0.86 | BRD4 (0.47) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL16627661 | 0.86 | DAO (0.51) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL16627801 | 0.86 | BRD4 (0.47) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL16627799 | 0.83 | BRD4 (0.45) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL16627651 | 0.82 | BRD4 (0.44) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL16627811 | 0.82 | BRD4 (0.44) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL16627641 | 0.81 | MEN1 (0.44) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL30740091 | 0.71 | KDR (0.60) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL28599651 | 0.71 | BRD4 (0.54) | BRD4DAODDOKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |