Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627574 | 0.87 | BRD4 (0.57) | BRD4KDM4EALDH1A1MAPTCYP1A2 | |
| SCHEMBL16627800 | 0.86 | BRD4 (0.47) | BRD4KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL16627661 | 0.86 | DAO (0.51) | BRD4KDM4EALDH1A1CYP1A2MEN1 | |
| SCHEMBL16627578 | 0.86 | BRD4 (0.47) | BRD4KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL16627799 | 0.83 | BRD4 (0.45) | BRD4KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL16627651 | 0.82 | BRD4 (0.44) | BRD4KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL16627641 | 0.81 | MEN1 (0.44) | BRD4KDM4EALDH1A1MAPTCYP1A2 | |
| SCHEMBL30740090 | 0.71 | KDM4E (0.60) | BRD4KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL28599651 | 0.71 | BRD4 (0.54) | BRD4KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL11178624 | 0.71 | KDM4E (0.60) | BRD4KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |