SCHEMBL16627978

SCHEMBL16627978

CC(=O)C/C(C)=N/c1cccc2cccnc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.44
POLB P06746 2/20 0.44
MAPT P10636 3/20 0.43
KDM4E B2RXH2 3/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
HTT P42858 2/20 0.43
PARP1 P09874 1/20 0.43
MEN1 O00255 1/20 0.43
GAA P10253 1/20 0.43
ALDH1A1 P00352 5/20 0.42
LMNA P02545 1/20 0.41
HPGD P15428 4/20 0.41
HSD17B10 Q99714 3/20 0.41
KDR P35968 2/20 0.41
MMP2 P08253 1/20 0.41
CHRM1 P11229 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21192707 1.00 TDP1 (0.44) TDP1POLBMAPTKDM4EKMT2A
SCHEMBL18543939 0.91 MAPT (0.47) TDP1POLBMAPTKDM4EKMT2A
SCHEMBL18543937 0.91 MAPT (0.47) TDP1POLBMAPTKDM4EKMT2A
SCHEMBL29105219 0.81 MMP2 (0.42) TDP1POLBMAPTKDM4EKMT2A
SCHEMBL28556486 0.78 MEN1 (0.40) TDP1POLBMAPTKDM4EKMT2A
Phenanthroline SCHEMBL7693062 0.77 TDP1 (0.61) TDP1POLBMAPTKDM4ESMN1; SMN2
SCHEMBL21192637 0.76 TDP1 (0.42) TDP1POLBMAPTKDM4EKMT2A
SCHEMBL21192639 0.76 TDP1 (0.42) TDP1POLBMAPTKDM4EKMT2A
Phenanthroline SCHEMBL27590762 0.76 TDP1 (0.59) TDP1POLBMAPTKDM4ESMN1; SMN2
SCHEMBL15224521 0.75 SCN2A (0.48) TDP1KDM4EKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3517553-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2023-11-08 EP claimed
US-10662268-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2020-05-26 US claimed
US-20190256623-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-08-22 US claimed
EP-3517553-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP claimed
EP-3517553-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2023-11-08 EP disclosed
US-10662268-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2020-05-26 US disclosed
US-20190256623-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-08-22 US disclosed
EP-3517553-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP disclosed
US-9469799-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-10-18 US disclosed
US-9469799-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-10-18 US disclosed
US-20150337190-A1 Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2015-11-26 US disclosed
US-20150337190-A1 Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2015-11-26 US disclosed
US-9139699-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-09-22 US disclosed
US-9139699-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-09-22 US disclosed
WO-2015050583-A1 METAL CONTAINING CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2015-04-09 WO disclosed