Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.63 |
| ▸ | REN | P00797 | 9/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27624890 | 0.84 | SLC15A2 (0.61) | SLC15A2RENERAP2ERAP1LNPEP | |
| SCHEMBL29352785 | 0.83 | SLC15A2 (0.92) | SLC15A2RENCYP3A4SLC7A5SLC6A5 | |
| SCHEMBL23312951 | 0.82 | SLC15A2 (0.61) | SLC15A2RENCYP3A4SLC7A5SLC6A5 | |
| SCHEMBL19051549 | 0.82 | SLC15A2 (0.56) | SLC15A2RENCYP3A4SLC7A5HRH1 | |
| SCHEMBL12711228 | 0.81 | REN (0.54) | SLC15A2RENERAP2ERAP1LNPEP | |
| SCHEMBL2197786 | 0.81 | SLC15A2 (0.72) | SLC15A2CYP3A4SLC7A5SLC6A5CA1 | |
| SCHEMBL30081493 | 0.81 | SLC15A2 (0.72) | SLC15A2CYP3A4SLC7A5SLC6A5CA1 | |
| SCHEMBL29379300 | 0.81 | SLC15A2 (0.66) | SLC15A2RENCYP3A4SLC7A5SLC6A5 | |
| SCHEMBL18862044 | 0.80 | CYP3A4 (0.57) | RENCYP3A4SLC7A5 | |
| SCHEMBL29271690 | 0.80 | SLC15A2 (0.77) | SLC15A2RENCYP3A4SLC7A5SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051052-A2 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2015-04-09 | — | — | WO | disclosed |