Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16628580 | 0.90 | TSHR (0.47) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5057290 | 0.87 | TSHR (0.49) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16628571 | 0.82 | TSHR (0.47) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL18140745 | 0.77 | TSHR (0.47) | TSHRTHRB | |
| SCHEMBL9358566 | 0.77 | TSHR (0.50) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27867536 | 0.77 | THRB (0.47) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL18139968 | 0.76 | TSHR (0.49) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| Ammonia Solution, Strong SCHEMBL28050132 | 0.76 | THRB (0.46) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16628507 | 0.75 | TSHR (0.45) | TSHRTHRBCA2 | |
| SCHEMBL18139067 | 0.75 | TSHR (0.47) | TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150126682-A1 | HYDROPHILIC MODIFIED ACRYLIC RESIN FILM | MITSUI CHEMICALS, INC. (JP) | 2015-05-07 | — | — | US | disclosed |
| EP-2860215-A1 | MODIFIED HYDROPHILIC ACRYLIC RESIN FILM | Mitsui Chemicals, Inc. (JP) | 2015-04-15 | — | — | EP | disclosed |