Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800 | 0.87 | LIPE (0.64) | LIPE | |
| SCHEMBL1589626 | 0.87 | LIPE (0.64) | LIPE | |
| SCHEMBL11801 | 0.87 | LIPE (0.64) | LIPE | |
| SCHEMBL12702000 | 0.87 | LIPE (0.64) | LIPE | |
| SCHEMBL1589629 | 0.87 | LIPE (0.64) | LIPE | |
| SCHEMBL12702274 | 0.87 | LIPE (0.64) | LIPE | |
| SCHEMBL1590201 | 0.83 | LIPE (0.68) | LIPE | |
| SCHEMBL1589278 | 0.83 | LIPE (0.68) | LIPE | |
| SCHEMBL1589280 | 0.83 | LIPE (0.68) | LIPE | |
| SCHEMBL1589276 | 0.83 | LIPE (0.68) | LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488493-B1 | SPIRO-CONDENSED CYCLOHEXANE DERIVATIVES AS HSL INHIBITORS USEFUL FOR THE TREATMENT OF DIABETES | HOFFMANN LA ROCHE (CH) | 2015-04-15 | — | — | EP | claimed |