Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 11/20 | 0.77 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.77 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3093912 | 0.91 | HSP90AA1 (0.85) | HSP90AA1HSP90AB1ADORA3CNR1DPP8 | |
| SCHEMBL3095799 | 0.88 | HSP90AA1 (0.76) | HSP90AA1HSP90AB1ADORA3NPSR1 | |
| SCHEMBL3093806 | 0.88 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1ADORA3 | |
| SCHEMBL16628713 | 0.87 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1ADORA3 | |
| SCHEMBL3093783 | 0.85 | HSP90AA1 (0.77) | HSP90AA1HSP90AB1CNR1DPP8DPP9 | |
| SCHEMBL3075281 | 0.85 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1DPP8DPP9DPP7 | |
| SCHEMBL3087837 | 0.83 | HSP90AA1 (0.76) | HSP90AA1HSP90AB1CNR1DPP8DPP9 | |
| SCHEMBL3093202 | 0.83 | HSP90AA1 (0.76) | HSP90AA1HSP90AB1DPP8DPP9DPP7 | |
| SCHEMBL3088591 | 0.81 | HSP90AA1 (0.73) | HSP90AA1HSP90AB1CNR1DPP8DPP9 | |
| SCHEMBL16628709 | 0.78 | HSP90AA1 (0.80) | HSP90AA1HSP90AB1ADORA3NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164833-B1 | Quinazolinamide derivatives useful for the treatment of tumour diseases | MERCK PATENT GMBH (DE) | 2015-04-15 | — | — | EP | claimed |
| EP-2164833-B1 | Quinazolinamide derivatives useful for the treatment of tumour diseases | MERCK PATENT GMBH (DE) | 2015-04-15 | — | — | EP | disclosed |