Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | GRK6 | P43250 | 1/20 | 0.30 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1960354 | 0.88 | KDM4E (0.36) | KDM4ESMN1; SMN2DRD2MAPK14BRD4 | |
| SCHEMBL2343626 | 0.87 | KDM4E (0.36) | KDM4ESMN1; SMN2DRD2DRD1MAPK14 | |
| SCHEMBL1961173 | 0.85 | KDM4E (0.35) | KDM4ESMN1; SMN2 | |
| SCHEMBL1961792 | 0.85 | KCNK3 (0.38) | KDM4ESMN1; SMN2MAPK14KCNK3 | |
| SCHEMBL3180975 | 0.80 | GRIN2B (0.37) | GRIN2BSMN1; SMN2GRK6 | |
| SCHEMBL3187760 | 0.78 | GRIN2B (0.37) | GRIN2BGRK6 | |
| SCHEMBL3542557 | 0.78 | GRIN2B (0.39) | GRIN2BGRIN1GRK6 | |
| SCHEMBL3191507 | 0.76 | HCRTR1 (0.37) | GRIN2B | |
| SCHEMBL1958077 | 0.75 | GAA (0.43) | SMN1; SMN2MAPK14P2RX7 | |
| SCHEMBL1959936 | 0.75 | ADORA2B (0.32) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161273-B1 | Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment | LEUVEN K U RES & DEV (BE) | 2015-04-15 | — | — | EP | claimed |