Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16628833 | 1.00 | ADRB3 (0.33) | ADRB3ADRA2BADRA2CCTSBMEN1 | |
| SCHEMBL2837626 | 0.87 | CTSB (0.31) | CTSB | |
| SCHEMBL2837629 | 0.87 | CTSB (0.31) | CTSB | |
| SCHEMBL6760157 | 0.87 | CTSB (0.31) | CTSB | |
| SCHEMBL8245129 | 0.87 | CTSB (0.31) | CTSB | |
| SCHEMBL16239357 | 0.85 | CTSB (0.33) | CTSBMEN1KMT2A | |
| SCHEMBL14020644 | 0.84 | — | — | |
| SCHEMBL2158325 | 0.83 | ADRB3 (0.34) | ADRB3ADRA2BADRA2C | |
| SCHEMBL12730850 | 0.82 | ADRB3 (0.39) | ADRB3ADRA2BADRA2C | |
| SCHEMBL12777041 | 0.82 | ADRB3 (0.39) | ADRB3ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118091-B1 | PYRIMIDINE SUBSTITUTED MACROCYCLIC HCV INHIBITORS | JANSSEN SCIENCES IRELAND UC (IE) | 2015-04-15 | — | — | EP | disclosed |