Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123520 | 1.00 | MAPT (0.38) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL8259830 | 1.00 | MAPT (0.38) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL3115628 | 0.94 | ALDH1A1 (0.41) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL3124070 | 0.92 | ALDH1A1 (0.44) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL3120484 | 0.92 | ALDH1A1 (0.44) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL3111810 | 0.92 | ALDH1A1 (0.44) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL2133471 | 0.87 | — | — | |
| SCHEMBL3120777 | 0.81 | ALDH1A1 (0.40) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL12113872 | 0.81 | BLM (0.50) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL4329013 | 0.81 | CA1 (0.33) | MAPTALDH1A1CA1LTA4HCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051030-A2 | STABILIZED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-04-09 | — | — | WO | disclosed |