Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664520 | 0.79 | BRD4 (0.36) | BRD4PAX8HTR2CSLC6A4KDM4E | |
| SCHEMBL16384543 | 0.78 | HTR2C (0.47) | HTR2CSLC6A4CTSDCTSLCTSB | |
| SCHEMBL16629284 | 0.78 | GRN (0.49) | BRD4PAX8HTR2CSLC6A4KDM4E | |
| SCHEMBL15274080 | 0.77 | MALT1 (0.33) | CTSL | |
| SCHEMBL16629273 | 0.77 | BRD4 (0.35) | BRD4PAX8HTR2CSLC6A4KDM4E | |
| SCHEMBL18019577 | 0.73 | BRD4 (0.35) | BRD4PAX8TTK | |
| SCHEMBL16629291 | 0.71 | EGLN2 (0.39) | ALDH1A1TTK | |
| SCHEMBL15273703 | 0.71 | HTR2C (0.35) | HTR2CSLC6A4 | |
| SCHEMBL22445393 | 0.70 | CNR2 (0.32) | BRD4HTR2CSLC6A4 | |
| SCHEMBL16629271 | 0.70 | BRD4 (0.38) | BRD4PAX8HTR2CSLC6A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050989-A2 | MACROCYCLIC COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | CS THERAPEUTICS INC. (US) | 2015-04-09 | — | — | WO | disclosed |