Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12795937 | 0.93 | P2RX7 (0.39) | P2RX7USP2GAAHPGDALDH1A1 | |
| SCHEMBL1662663 | 0.88 | P2RX7 (0.48) | P2RX7USP2GAAHPGDALDH1A1 | |
| SCHEMBL1665293 | 0.88 | P2RX7 (0.51) | P2RX7USP2GAAHPGDALDH1A1 | |
| SCHEMBL1662826 | 0.87 | P2RX7 (0.42) | P2RX7USP2GAAHPGDALDH1A1 | |
| SCHEMBL1663508 | 0.86 | P2RX7 (0.43) | P2RX7USP2GAAHPGDALDH1A1 | |
| SCHEMBL1662639 | 0.86 | P2RX7 (0.43) | P2RX7USP2GAAHPGDALDH1A1 | |
| SCHEMBL1662692 | 0.86 | P2RX7 (0.41) | P2RX7USP2GAAHPGDALDH1A1 | |
| SCHEMBL1662691 | 0.86 | P2RX7 (0.41) | P2RX7USP2GAAHPGDALDH1A1 | |
| SCHEMBL1662677 | 0.86 | P2RX7 (0.43) | P2RX7USP2GAAHPGDALDH1A1 | |
| SCHEMBL12795935 | 0.86 | P2RX7 (0.40) | P2RX7USP2GAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | claimed |
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |