⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17362624 | 0.79 | — | — | |
| SCHEMBL3675779 | 0.74 | CYP11B1 (0.35) | — | |
| SCHEMBL2510512 | 0.73 | — | — | |
| SCHEMBL8154592 | 0.73 | — | — | |
| SCHEMBL22482632 | 0.73 | — | — | |
| SCHEMBL31027288 | 0.73 | — | — | |
| SCHEMBL7789608 | 0.73 | — | — | |
| SCHEMBL6957377 | 0.73 | — | — | |
| SCHEMBL245286 | 0.71 | HTT (0.62) | — | |
| SCHEMBL29799259 | 0.71 | DGAT1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111333840-B | Intrinsic self-repairing amino acid polymer and preparation method thereof | 安徽东凯生物科技股份有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-113942983-A | Preparation method of novel carbon nitride-based material combining copolymerization and thermal induction | 陕西科技大学 | 2022-01-18 | — | — | CN | claimed |
| CN-111333840-A | Amino acid polymer with intrinsic self-repairing property and preparation method thereof | 刘云晖 | 2020-06-26 | — | — | CN | claimed |
| CN-111333871-A | Intrinsic self-repairing zwitterionic hydrogel and preparation method thereof | 刘云晖 | 2020-06-26 | — | — | CN | claimed |
| EP-2529388-B1 | FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY | MICROMASS LTD (GB) | 2019-10-23 | — | — | EP | claimed |
| CN-1976922-B | 4-amino-5-cyanopyrimidine derivatives | OTSUKA PHARMA CO LTD | 2012-09-05 | — | — | CN | claimed |
| WO-2011116933-A1 | PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED 4-AMINO-5-CYANOPYRIMIDINES | LONZA LTD (CH) | 2011-09-29 | — | — | WO | claimed |
| EP-2368883-A1 | Process for the preparation of 2-substituted 4-amino-5-cyanopyrimidines | Lonza Ltd. (CH) | 2011-09-28 | — | — | EP | claimed |
| US-7989446-B2 | 4-amino 5-cyanopyrimidine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-02 | — | — | US | claimed |
| US-20110009620-A1 | 4-Amino-5-cyanopyrimidine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. | 2011-01-13 | — | — | US | claimed |
| US-20080182854-A1 | 4-Amino-5-Cyanopyrimidine Derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-07-31 | — | — | US | claimed |
| EP-1740574-B1 | 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2007-06-27 | — | — | EP | claimed |
| CN-1976922-A | 4-amino-5-cyanopyrimidine derivatives | OTSUKA PHARMA CO LTD (JP) | 2007-06-06 | — | — | CN | claimed |
| EP-1740574-A2 | 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES | Otsuka Pharmaceutical Company, Limited (JP) | 2007-01-10 | — | — | EP | claimed |
| WO-2005105778-A2 | 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-11-10 | — | — | WO | claimed |
| EP-1086106-B1 | FUROPYRIDINE DERIVATIVES AND THEIR THERAPEUTICAL USE | DARWIN DISCOVERY LTD (GB) | 2003-08-20 | — | — | EP | claimed |
| EP-1086106-A1 | FUROPYRIDINE DERIVATIVES AND THEIR THERAPEUTICAL USE | Darwin Discovery Limited (GB) | 2001-03-28 | — | — | EP | claimed |
| US-6169090-B1 | FOR INHIBITION OF PHOSPHODIESTERASE IV | DARWIN DISCOVERY, LTD. (GB) | 2001-01-02 | — | — | US | claimed |
| WO-1999064423-A1 | FUROPYRIDINE DERIVATIVES AND THEIR THERAPEUTICAL USE | DARWIN DISCOVERY LIMITED (GB) | 1999-12-16 | — | — | WO | claimed |
| CN-1128024-A | Process for preparing substituted 4, 6-diamino-5-cyanopyrimidines | CIBA GEIGY AG (CH) | 1996-07-31 | — | — | CN | claimed |